title

FoundMyFitness

Rhonda Patrick, Ph.D.

573
Followers
2.1K
Plays
FoundMyFitness
FoundMyFitness

FoundMyFitness

Rhonda Patrick, Ph.D.

573
Followers
2.1K
Plays
OVERVIEWEPISODESYOU MAY ALSO LIKE

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About Us

Promoting strategies to increase healthspan, well-being, cognitive and physical performance through deeper understandings of biology.

Latest Episodes

Sauna Use as an Exercise Mimetic for Heart and Healthspan

This podcast is the audio from a presentation Dr. Rhonda Patrick gave on how the sauna may be an exercise mimetic for heat health and healthspan. Sauna use has emerged as a means to increase lifespan and improve overall health, based on compelling data from observational, interventional, and mechanistic studies. Listen in to find out more. Click here to get the episode show notes and video. Watch the episode with cardiologist and sauna scientist Dr. Jari Laukkanen. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about how to support the podcast.

46 MINSEP 16
Comments
Sauna Use as an Exercise Mimetic for Heart and Healthspan

Exercise as a Treatment for Depression

In this short episode, Dr. Patrick discusses some of the compelling science including observational studies, randomized controlled trials, and human mechanistic studies that suggests exercise is a powerful tool for preventing or managing the symptoms of depression and mental illness. Moreover, she talks about the specific types of exercise and exercise parameters that evidence suggests might be the most helpful for depression. This podcast started its life as a video, so make sure to check out the full video or the references and episode notes on the episode page. Click here to get this episode's show notes and video. Click here to visit the in-depth depression topic page. See the full interview with Dr. Charles Raison. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about how to support the podcast and access the premium members benefits.

17 MINAUG 3
Comments
Exercise as a Treatment for Depression

Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging

Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health. In this episode, we dive deep into the world of telomeres, the length of which is one of the useful biomarkers scientists have for getting a sense of the differences between how individuals or groups of individuals age. Telomere shortening is both a cause and a symptom of aging and plays key roles in not only how long we live, but in how well. Lifestyle factors such as poor nutrition and smoking can accelerate telomere shortening by generating oxidative stress and inflammation. Click here to get this episode's show notes and transcript. Watch this episode's highlights on the FMF Clips channel. Did you enjoy this podcast? It was brought to you by ...

73 MINJUN 10
Comments
Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging

Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System

Matthew Walker, Ph.D., is a professor of neuroscience and psychology at the University of California, Berkeley, and serves as the Director of the Center for Human Sleep Science. Formerly, Dr. Walker served as a professor of psychiatry at the Harvard Medical School. Walker's research examines the impact of sleep on human health and disease. One area of interest focuses on identifying "vulnerability windows" during a person's life that make them more susceptible to amyloid-beta deposition from loss of slow wave sleep and, subsequently, Alzheimer's disease later in life. Dr. Walker earned his undergraduate degree in neuroscience from the University of Nottingham, UK, and his Ph.D. in neurophysiology from the Medical Research Council, London, UK. He is the author of the New York Times best-selling book Why We Sleep: Unlocking the Power of Sleep and Dreams. Click here to get this episode's show notes and transcript. Watch nearly twenty-seven episode highlights on the new FMF Clips channe...

167 MINMAR 1
Comments
Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System

Fasting Q&A with Dr. Rhonda Patrick and Mike Maser

This episode features a Q&A session with Dr. Rhonda Patrick. The questions were sourced from social media followers of both FoundMyFitness and also Zero Fasting Tracker, a convenient mobile app used widely in the fasting community for logging. In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: What effects coffee, supplements, and amino acids have on fasting Whether one method of fasting is more beneficial than others What effect the consumption of exogenous ketones have on fasting Whether it is good to exercise while fasting The ideal way to break a fast How fasting affects muscle mass How fasting plays a role in the growth-longevity tradeoff ... and more! Watch the video of the conversion or get the timeline here. Learn how you can support the FoundMyFitness podcast for as little or as much as you like by clicking here.

49 MINJAN 9
Comments
Fasting Q&A with Dr. Rhonda Patrick and Mike Maser

Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

Dale E. Bredesen, M.D., is a professor of neurology at the Easton Laboratories for Neurodegenerative Disease Research at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Dr. Bredesen's laboratory focuses on identifying and understanding basic mechanisms underlying the neurodegenerative process and the translation of this knowledge into effective treatments for Alzheimer's disease and other neurodegenerative conditions. He has collaborated on the publication of more than 220 academic research papers. His work has culminated in the development of a protocol called ReCODE – reversal of cognitive decline – currently used by over 3,000 patients with the goal of not just preventing, but reversing Alzheimer's disease and mild cognitive impairment. Click here to get the episode's show notes and transcript. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about ho...

74 MIN2018 OCT 1
Comments
Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD

This podcast is a spectacular round two podcast with Dr. Valter Longo. Dr. Longo is the current director of the longevity institute at the University of Southern California and also director of the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy. Dr. Longo’s research focuses understanding the biological mechanisms that regulate the aging process, the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. In this episode, we discuss... What two seminal studies on chronic caloric restriction in primates from the 80s teach us about caloric restriction as a preventer of age-related disease, and how the effects of caloric restriction may actually be stronger when the diet that is being restricted is an unhealthy one – similar, in some ways, to the typical western diet. How certain macronutrients influence the insulin/IGF-1/growth hormone axis interact to ...

77 MIN2018 JUL 9
Comments
Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD

Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Charles Raison, M.D. is a professor at the School of Human Ecology at the University of Wisconsin-Madison and Founding Director of the Center for Compassion Studies in the College of Social and Behavioral Sciences at the University of Arizona. Dr. Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well as the effect of heat stress as a potentially therapeutic intervention major depressive disorder. In this nearly 2-hour episode, we discuss the extremely dynamic interaction that the immune system has with mood, behavior, and the brain, as well as the potential that whole-body hyperthermia, a research technique mostly indistinguishable from sauna use, may have for the treatment of clinical depression. Additionally, we also talk about…. How depression as a disease may be subdivided based on whethe...

118 MIN2018 MAR 20
Comments
Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors

Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer’s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He's held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research. In this episode, we discuss... The effects of a low protein, cyclic ketogenic diet beginning in midlife (12 months of age) in male mice. The result? Increased healthspan and improved memory. Dr. Verdin explains how the cyclic ketogenic diet decreased insulin, IGF-1, and mTOR signaling and decreased fatty acid synthesis, and increased PPAR-alpha (which promotes beta-oxida...

63 MIN2017 DEC 13
Comments
Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors

Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies

This is a nearly 2-hour round 2 episode with none other than Dr. Satchin Panda of the Salk Institute! At nearly two hours of dialog, this episode touches on a lot of material but has a special focus on practical implementation of time-restricted eating. Put another way, I kept a list of a lot of questions that seem to keep coming up and present them directly to Satchin. We talk about dealing with shift work, black coffee when fasting, and some of the distinctions between Satchin's approach to time-restricted eating which is influenced by his deep background in circadian biology and more conventional protocols like 16:8 that many people are familiar with. In addition to these important and very practical how-to tidbits, we dive into lots of interesting new territory as well, including... How human anecdote and animal evidence suggests time-restricted feeding may be especially useful for gut-related issues, including inflammatory bowel disease and acid reflux. The fascinating way Dr. ...

122 MIN2017 OCT 31
Comments
Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies

Latest Episodes

Sauna Use as an Exercise Mimetic for Heart and Healthspan

This podcast is the audio from a presentation Dr. Rhonda Patrick gave on how the sauna may be an exercise mimetic for heat health and healthspan. Sauna use has emerged as a means to increase lifespan and improve overall health, based on compelling data from observational, interventional, and mechanistic studies. Listen in to find out more. Click here to get the episode show notes and video. Watch the episode with cardiologist and sauna scientist Dr. Jari Laukkanen. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about how to support the podcast.

46 MINSEP 16
Comments
Sauna Use as an Exercise Mimetic for Heart and Healthspan

Exercise as a Treatment for Depression

In this short episode, Dr. Patrick discusses some of the compelling science including observational studies, randomized controlled trials, and human mechanistic studies that suggests exercise is a powerful tool for preventing or managing the symptoms of depression and mental illness. Moreover, she talks about the specific types of exercise and exercise parameters that evidence suggests might be the most helpful for depression. This podcast started its life as a video, so make sure to check out the full video or the references and episode notes on the episode page. Click here to get this episode's show notes and video. Click here to visit the in-depth depression topic page. See the full interview with Dr. Charles Raison. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about how to support the podcast and access the premium members benefits.

17 MINAUG 3
Comments
Exercise as a Treatment for Depression

Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging

Elissa Epel, PhD, is a Professor in the Department of Psychiatry at the University of California, San Francisco where she serves as the director of the Aging, Metabolism, and Emotions Center. Her research centers on the mechanisms of healthy aging and the associations between stress, telomere length, addiction, eating, and metabolic health. In this episode, we dive deep into the world of telomeres, the length of which is one of the useful biomarkers scientists have for getting a sense of the differences between how individuals or groups of individuals age. Telomere shortening is both a cause and a symptom of aging and plays key roles in not only how long we live, but in how well. Lifestyle factors such as poor nutrition and smoking can accelerate telomere shortening by generating oxidative stress and inflammation. Click here to get this episode's show notes and transcript. Watch this episode's highlights on the FMF Clips channel. Did you enjoy this podcast? It was brought to you by ...

73 MINJUN 10
Comments
Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging

Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System

Matthew Walker, Ph.D., is a professor of neuroscience and psychology at the University of California, Berkeley, and serves as the Director of the Center for Human Sleep Science. Formerly, Dr. Walker served as a professor of psychiatry at the Harvard Medical School. Walker's research examines the impact of sleep on human health and disease. One area of interest focuses on identifying "vulnerability windows" during a person's life that make them more susceptible to amyloid-beta deposition from loss of slow wave sleep and, subsequently, Alzheimer's disease later in life. Dr. Walker earned his undergraduate degree in neuroscience from the University of Nottingham, UK, and his Ph.D. in neurophysiology from the Medical Research Council, London, UK. He is the author of the New York Times best-selling book Why We Sleep: Unlocking the Power of Sleep and Dreams. Click here to get this episode's show notes and transcript. Watch nearly twenty-seven episode highlights on the new FMF Clips channe...

167 MINMAR 1
Comments
Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System

Fasting Q&A with Dr. Rhonda Patrick and Mike Maser

This episode features a Q&A session with Dr. Rhonda Patrick. The questions were sourced from social media followers of both FoundMyFitness and also Zero Fasting Tracker, a convenient mobile app used widely in the fasting community for logging. In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: What effects coffee, supplements, and amino acids have on fasting Whether one method of fasting is more beneficial than others What effect the consumption of exogenous ketones have on fasting Whether it is good to exercise while fasting The ideal way to break a fast How fasting affects muscle mass How fasting plays a role in the growth-longevity tradeoff ... and more! Watch the video of the conversion or get the timeline here. Learn how you can support the FoundMyFitness podcast for as little or as much as you like by clicking here.

49 MINJAN 9
Comments
Fasting Q&A with Dr. Rhonda Patrick and Mike Maser

Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

Dale E. Bredesen, M.D., is a professor of neurology at the Easton Laboratories for Neurodegenerative Disease Research at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Dr. Bredesen's laboratory focuses on identifying and understanding basic mechanisms underlying the neurodegenerative process and the translation of this knowledge into effective treatments for Alzheimer's disease and other neurodegenerative conditions. He has collaborated on the publication of more than 220 academic research papers. His work has culminated in the development of a protocol called ReCODE – reversal of cognitive decline – currently used by over 3,000 patients with the goal of not just preventing, but reversing Alzheimer's disease and mild cognitive impairment. Click here to get the episode's show notes and transcript. Did you enjoy this podcast? It was brought to you by people like you! Click here to visit our crowdsponsor page where you can learn more about ho...

74 MIN2018 OCT 1
Comments
Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD

This podcast is a spectacular round two podcast with Dr. Valter Longo. Dr. Longo is the current director of the longevity institute at the University of Southern California and also director of the Oncology and Longevity Program at the Institute of Molecular Oncology Foundation in Milan, Italy. Dr. Longo’s research focuses understanding the biological mechanisms that regulate the aging process, the role of fasting and diet in longevity and healthspan in humans as well as metabolic fasting therapies for the treatment of human diseases. In this episode, we discuss... What two seminal studies on chronic caloric restriction in primates from the 80s teach us about caloric restriction as a preventer of age-related disease, and how the effects of caloric restriction may actually be stronger when the diet that is being restricted is an unhealthy one – similar, in some ways, to the typical western diet. How certain macronutrients influence the insulin/IGF-1/growth hormone axis interact to ...

77 MIN2018 JUL 9
Comments
Dr. Valter Longo on Resetting Autoimmunity and Rejuvenating Systems with Prolonged Fasting & the FMD

Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Charles Raison, M.D. is a professor at the School of Human Ecology at the University of Wisconsin-Madison and Founding Director of the Center for Compassion Studies in the College of Social and Behavioral Sciences at the University of Arizona. Dr. Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well as the effect of heat stress as a potentially therapeutic intervention major depressive disorder. In this nearly 2-hour episode, we discuss the extremely dynamic interaction that the immune system has with mood, behavior, and the brain, as well as the potential that whole-body hyperthermia, a research technique mostly indistinguishable from sauna use, may have for the treatment of clinical depression. Additionally, we also talk about…. How depression as a disease may be subdivided based on whethe...

118 MIN2018 MAR 20
Comments
Dr. Charles Raison on Depression, the Immune-Brain Interface & Whole-Body Hyperthermia

Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors

Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabolism and diet in aging and on the chronic diseases of aging, including Alzheimer’s, proteins that play a central role in linking caloric restriction to increased healthspan, and more recently a topic near and dear to many of you, ketogenesis. He's held faculty positions at the University of Brussels, the NIH and the Picower Institute for Medical Research. In this episode, we discuss... The effects of a low protein, cyclic ketogenic diet beginning in midlife (12 months of age) in male mice. The result? Increased healthspan and improved memory. Dr. Verdin explains how the cyclic ketogenic diet decreased insulin, IGF-1, and mTOR signaling and decreased fatty acid synthesis, and increased PPAR-alpha (which promotes beta-oxida...

63 MIN2017 DEC 13
Comments
Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors

Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies

This is a nearly 2-hour round 2 episode with none other than Dr. Satchin Panda of the Salk Institute! At nearly two hours of dialog, this episode touches on a lot of material but has a special focus on practical implementation of time-restricted eating. Put another way, I kept a list of a lot of questions that seem to keep coming up and present them directly to Satchin. We talk about dealing with shift work, black coffee when fasting, and some of the distinctions between Satchin's approach to time-restricted eating which is influenced by his deep background in circadian biology and more conventional protocols like 16:8 that many people are familiar with. In addition to these important and very practical how-to tidbits, we dive into lots of interesting new territory as well, including... How human anecdote and animal evidence suggests time-restricted feeding may be especially useful for gut-related issues, including inflammatory bowel disease and acid reflux. The fascinating way Dr. ...

122 MIN2017 OCT 31
Comments
Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies