title

Wired to be Weird

Ian McLaughlin & Bo Allen

4
Followers
7
Plays
Wired to be Weird
Wired to be Weird

Wired to be Weird

Ian McLaughlin & Bo Allen

4
Followers
7
Plays
OVERVIEWEPISODESYOU MAY ALSO LIKE

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About Us

Tearing down the pay-wall that separates people from the research they pay for

Latest Episodes

Fountains of Youth? Metformin, Nicotinamide Riboside & Mononucleotide, Elysium & ChromaDex, and Caloric Restriction

Bo and I discuss some of the leading candidates for extending both human lifespan and “health-span”, including metformin, nicotinamide riboside & nicotinamide mononucleotide, and caloric restriction. We also chat about some of the companies working in this area, as well as novel business models that may or may not be a strategy to enable rigorous research of something as difficult to study as human lifespan.

76 MINMAY 10
Comments
Fountains of Youth? Metformin, Nicotinamide Riboside & Mononucleotide, Elysium & ChromaDex, and Caloric Restriction

How to Grow a Baby

We delve into how lifestyle factors, sleep, mood, and various kinds of pollution can influence the brain development of a child. We also chat about some ways to minimize the likelihood that those factors have a negative effect on development.

-1 sMAR 22
Comments
How to Grow a Baby

Inheriting Politics

In preparation for the upcoming mid-term elections in the United States (REMEMBER TO VOTE ON NOVEMBER 6TH !), Bo and I chat about how much of a person’s politics are inherited genetically from their parents, as well as some companies that are entirely devoted to trying to make you vote in a certain way. I learned quite a bit prepping for this conversation, and suffice it to say that I was pretty surprised with what I learned. Note about the recording: if you can’t tell, we’re using a new audio set-up (thank you Patreon & Twitter supporters!!!). While we have gotten rid of some of the ambient noise – at least as much noise as you can in a Philly apartment – we’re clearly lacking pop-filters on this recording. So, apologies for the heavy Ps and Bs on this one; a pop-filter has been ordered.

-1 s2018 NOV 4
Comments
Inheriting Politics

The Beast Inside Us All

In the last episode, Bo and I chatted about two famous experiments - and how they've been re-interpreted over time. In this episode, we discuss one of them in greater detail - as well as what we can learn about how science, society, and government can influence one another.

63 MIN2018 SEP 10
Comments
The Beast Inside Us All

Marshmallows & Prisoners: two classic studies are redefined

Today, Bo and I chatted about two of the most widely known studies of human behavior in modern history - the Marshmallow Test and the Stanford Prisoner Experiment. New data and interviews have emerged that fundamentally redefine how we ought to interpret these classic studies. Also, we discuss whether kids have been getting better or worse at delaying gratification since the 1960s. It's a fun conversation, and we hope you enjoy!References (in short-hand; I'm swamped right now!):Consent form for Prison Life Study, August 1971:http://pdf.prisonexp.org/consent.pdfStanford Prison Experiment recordings:https://searchworks.stanford.edu/view/jh477zg7277https://purl.stanford.edu/wn708sg00502018 Carlson, Mischel - Cohort effects in children's delay of gratificationBen Blum's Incredibly Awesome Entry about the Stanford Prisoner Experiment:https://medium.com/s/trustissues/the-lifespan-of-a-lie-d869212b1f622018 Jessica McCrory Calarco, Atlantic - Why rich kids are so good at the marshmallow tes...

56 MIN2018 JUL 13
Comments
Marshmallows & Prisoners: two classic studies are redefined

Laurel & Yanni, migraine treatment, Alzheimers & exercise, universality of music

Another multi-topic episode. We discuss the recent approval of a new treatment for migraines, then some evidence suggesting a certain kind of exercise may be therapeutic for Alzheimer's disease, and finally some work that suggests there may be universal & cross-cultural features of music. We open, however, on the debate between the Laurel & Yanni people.

56 MIN2018 MAY 29
Comments
Laurel & Yanni, migraine treatment, Alzheimers & exercise, universality of music

Do Humans Use Pheromones?

Bo and I discuss the evidence that supports and refutes a role played by pheromones in guiding human attraction - as well as a potential role played by the immune system in making some people more attractive than others, guiding human attraction and even human evolution.

47 MIN2018 MAR 26
Comments
Do Humans Use Pheromones?

NeuroByte - IQ & Illness + A Cause of Dyslexia

We discuss a study at least partly monitored by one of Ian's college mentors that explored whether there might be a relationship between high IQ scores and psychiatric & physiological diagnoses. We then discuss a study that blew Ian's mind, showing that some cases of dyslexia may be attributable to some unique structures within the eyes.

25 MIN2018 FEB 8
Comments
NeuroByte - IQ & Illness + A Cause of Dyslexia

NeuroByte - Neurons talking like viruses & is your mind's eye blind?

Bo and I discuss two science stories from the recent past. One is a discovery that neurons are capable of trading genetic material to one another directly - meaning, that one neuron can express a gene, transcribe it into RNA, and then send it to another neuron in which that gene wasn't expressed. Second, we discuss a possible condition termed "aphantasia", which describes a population of people who are entirely incapable of visualizing an imagined image.

34 MIN2018 JAN 24
Comments
NeuroByte - Neurons talking like viruses & is your mind's eye blind?

Is addiction a disease or a disorder? (Part 2)

Why are some so skeptical of the disease model of addiction, while institutions like NIDA and the NIH embrace it? Should the NIH adjust its perspective? And what is Ian's opinion?

52 MIN2018 JAN 8
Comments
Is addiction a disease or a disorder? (Part 2)

Latest Episodes

Fountains of Youth? Metformin, Nicotinamide Riboside & Mononucleotide, Elysium & ChromaDex, and Caloric Restriction

Bo and I discuss some of the leading candidates for extending both human lifespan and “health-span”, including metformin, nicotinamide riboside & nicotinamide mononucleotide, and caloric restriction. We also chat about some of the companies working in this area, as well as novel business models that may or may not be a strategy to enable rigorous research of something as difficult to study as human lifespan.

76 MINMAY 10
Comments
Fountains of Youth? Metformin, Nicotinamide Riboside & Mononucleotide, Elysium & ChromaDex, and Caloric Restriction

How to Grow a Baby

We delve into how lifestyle factors, sleep, mood, and various kinds of pollution can influence the brain development of a child. We also chat about some ways to minimize the likelihood that those factors have a negative effect on development.

-1 sMAR 22
Comments
How to Grow a Baby

Inheriting Politics

In preparation for the upcoming mid-term elections in the United States (REMEMBER TO VOTE ON NOVEMBER 6TH !), Bo and I chat about how much of a person’s politics are inherited genetically from their parents, as well as some companies that are entirely devoted to trying to make you vote in a certain way. I learned quite a bit prepping for this conversation, and suffice it to say that I was pretty surprised with what I learned. Note about the recording: if you can’t tell, we’re using a new audio set-up (thank you Patreon & Twitter supporters!!!). While we have gotten rid of some of the ambient noise – at least as much noise as you can in a Philly apartment – we’re clearly lacking pop-filters on this recording. So, apologies for the heavy Ps and Bs on this one; a pop-filter has been ordered.

-1 s2018 NOV 4
Comments
Inheriting Politics

The Beast Inside Us All

In the last episode, Bo and I chatted about two famous experiments - and how they've been re-interpreted over time. In this episode, we discuss one of them in greater detail - as well as what we can learn about how science, society, and government can influence one another.

63 MIN2018 SEP 10
Comments
The Beast Inside Us All

Marshmallows & Prisoners: two classic studies are redefined

Today, Bo and I chatted about two of the most widely known studies of human behavior in modern history - the Marshmallow Test and the Stanford Prisoner Experiment. New data and interviews have emerged that fundamentally redefine how we ought to interpret these classic studies. Also, we discuss whether kids have been getting better or worse at delaying gratification since the 1960s. It's a fun conversation, and we hope you enjoy!References (in short-hand; I'm swamped right now!):Consent form for Prison Life Study, August 1971:http://pdf.prisonexp.org/consent.pdfStanford Prison Experiment recordings:https://searchworks.stanford.edu/view/jh477zg7277https://purl.stanford.edu/wn708sg00502018 Carlson, Mischel - Cohort effects in children's delay of gratificationBen Blum's Incredibly Awesome Entry about the Stanford Prisoner Experiment:https://medium.com/s/trustissues/the-lifespan-of-a-lie-d869212b1f622018 Jessica McCrory Calarco, Atlantic - Why rich kids are so good at the marshmallow tes...

56 MIN2018 JUL 13
Comments
Marshmallows & Prisoners: two classic studies are redefined

Laurel & Yanni, migraine treatment, Alzheimers & exercise, universality of music

Another multi-topic episode. We discuss the recent approval of a new treatment for migraines, then some evidence suggesting a certain kind of exercise may be therapeutic for Alzheimer's disease, and finally some work that suggests there may be universal & cross-cultural features of music. We open, however, on the debate between the Laurel & Yanni people.

56 MIN2018 MAY 29
Comments
Laurel & Yanni, migraine treatment, Alzheimers & exercise, universality of music

Do Humans Use Pheromones?

Bo and I discuss the evidence that supports and refutes a role played by pheromones in guiding human attraction - as well as a potential role played by the immune system in making some people more attractive than others, guiding human attraction and even human evolution.

47 MIN2018 MAR 26
Comments
Do Humans Use Pheromones?

NeuroByte - IQ & Illness + A Cause of Dyslexia

We discuss a study at least partly monitored by one of Ian's college mentors that explored whether there might be a relationship between high IQ scores and psychiatric & physiological diagnoses. We then discuss a study that blew Ian's mind, showing that some cases of dyslexia may be attributable to some unique structures within the eyes.

25 MIN2018 FEB 8
Comments
NeuroByte - IQ & Illness + A Cause of Dyslexia

NeuroByte - Neurons talking like viruses & is your mind's eye blind?

Bo and I discuss two science stories from the recent past. One is a discovery that neurons are capable of trading genetic material to one another directly - meaning, that one neuron can express a gene, transcribe it into RNA, and then send it to another neuron in which that gene wasn't expressed. Second, we discuss a possible condition termed "aphantasia", which describes a population of people who are entirely incapable of visualizing an imagined image.

34 MIN2018 JAN 24
Comments
NeuroByte - Neurons talking like viruses & is your mind's eye blind?

Is addiction a disease or a disorder? (Part 2)

Why are some so skeptical of the disease model of addiction, while institutions like NIDA and the NIH embrace it? Should the NIH adjust its perspective? And what is Ian's opinion?

52 MIN2018 JAN 8
Comments
Is addiction a disease or a disorder? (Part 2)