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TGen Talks

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TGen Talks
TGen Talks

TGen Talks

TGen

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About Us

TGen Talks explores the human genome to tackle the latest science and discoveries in cancer, neurological disorders, rare diseases, metabolic disorders and infectious disease. Learn about causes and potential cures in our monthly podcast!

Latest Episodes

Episode 19: Breathing Life Into Research

The offer of help to a family friend created a serendipitous chain of events that led Dr. Nick Banovich to study Idiopathic Pulmonary Fibrosis (IPF). IPF is a type of lung disease that scars the lungs and as it worsens makes it for the lungs to take in enough oxygen. In episode 19 ofTGen Talks, Dr. Banovich explains how the right collaboration and today's technology make it possible to examine individual cells, rather than a mash-up of many cells from a tissue sample, to identify gene expression changes associated with IPF, work that is breathing new life into research surrounding IPF.

10 MIN1 days ago
Comments
Episode 19: Breathing Life Into Research

Episode 18: Stirring Up A Whole Lot of Science Around Valley Fever

TGen North's Dr. David Engelthaler discusses Valley Fever. We learn why Arizona - with nearly 65% of all Valley Fever cases intheU.S.- is the perfect hotbed for research into this debilitating and potentially lethal disease, and how TGen North is tracking this warm-climate invader and adapting today's technology to provide much needed answers to this age-old problem.

10 MINAUG 21
Comments
Episode 18: Stirring Up A Whole Lot of Science Around Valley Fever

Episode 17: A Deeper Look at Proteomics

Patrick Pirrotte, Ph.D., Assistant Professor of the Cancer and Cell Biology Division and the Director of TGen's Collaborative Center for Translational Mass Spectrometry discusses the role of proteomics in cancer research, and finding new targets for cancer treatment.

4 MINJUL 20
Comments
Episode 17: A Deeper Look at Proteomics

Episode 16: Comparative Oncology Provides Deeper Insight into Cancer

TGen Assistant Professor, Dr. Will Hendricks, discusses comparative oncology, a field of study that in recent years has gained in popularity, as it seeks to integrate information from naturally occurring cancers in pets into what we know about the biology of cancer in humans.

9 MINJUN 21
Comments
Episode 16: Comparative Oncology Provides Deeper Insight into Cancer

Episode 15: MindCrowd—A Study on how the Healthy Brain Works

MindCrowd, launched seven years ago by Dr. Matthew Huentelman, studies the healthy brain. At its core, MindCrowd offers a new way approach scientific research to learn how the brain functions and how genetics influences memory.

11 MINMAY 30
Comments
Episode 15: MindCrowd—A Study on how the Healthy Brain Works

Tiny Microbes A Big Deal for Dr. Sarah Highlander

Microbes out-number the genes in your DNA by more than 1,000 to 1 and together they make up what is known as your microbiome. TGen’s Dr. Sarah K. Highlander, a research professor in the Pathogen and Microbiome Division at TGen North and director of the Clinical Microbiome Service Center, works to understand the microbiome and how it is helping scientists better understand cancer, diabetes and a host of other conditions, including traveler’s diarrhea.

9 MINAPR 17
Comments
Tiny Microbes A Big Deal for Dr. Sarah Highlander

Episode 13: AI and Big Data with Dr. Glen Otero

Dr. Glen Otero, a 20 year veteran of life science industry and an expert in high-performance computing, discusses artificial intelligence, or A.I., and how it addresses the computational needs of the biomedical research community by executing tasks more rapidly and without human error in a fraction of the time. Today, A.I. is used to process complex genomic data sets to accelerate delivery of personalized treatments for cancer and other diseases by turning raw genomic data —such as a human genome sequence— into usable information to predict disease patterns and treatment outcomes.

8 MINMAR 21
Comments
Episode 13: AI and Big Data with Dr. Glen Otero

Episode 12: TGen Talks — Tracking Neurodegenerative Disorders With Biomarkers

In medicine, a biomarker is anything used to determine the presence or development of a particular disease or biological state. They can be used to determine if an injury or disease has occurred, or even if a therapy is working. In this episode, Dr. Kendall Van Keuren-Jensen, a Professor in TGen Neurogenomics Division and Co-Director of TGen’s Center for Noninvasive Diagnostics, discusses how her team is working on ways to use biomarkers — in this case the molecular readout of RNA — as a non-invasive method for studying and treating complex diseases, such as those that affect the nervous system.

9 MINJAN 30
Comments
Episode 12: TGen Talks — Tracking Neurodegenerative Disorders With Biomarkers

Episode 11: Outside Influence: Stimuli, Epigenomics, and Changing Cell Behavior

Nature vs. nurture? How about nature and nature? Dr. Candace Lewis, a postdoctoral fellow in the Huentelman lab at TGen, walks us through a biological regulatory framework known as epigenomics that changes the behavior of our cells due to our life experiences. Dr. Lewis also discusses the resurgence in psychedelic assisted therapy to treat depression and trauma, and her work in Autism.

8 MIN2018 DEC 14
Comments
Episode 11: Outside Influence: Stimuli, Epigenomics, and Changing Cell Behavior

Episode 10: TGen Talks Takeover - Your Best Advice

Helios Scholar Mario Mosqueda asked 10 TGen scientists for their best career advice in an insightful discussion on charting a path in science.

19 MIN2018 OCT 26
Comments
Episode 10: TGen Talks Takeover - Your Best Advice

Latest Episodes

Episode 19: Breathing Life Into Research

The offer of help to a family friend created a serendipitous chain of events that led Dr. Nick Banovich to study Idiopathic Pulmonary Fibrosis (IPF). IPF is a type of lung disease that scars the lungs and as it worsens makes it for the lungs to take in enough oxygen. In episode 19 ofTGen Talks, Dr. Banovich explains how the right collaboration and today's technology make it possible to examine individual cells, rather than a mash-up of many cells from a tissue sample, to identify gene expression changes associated with IPF, work that is breathing new life into research surrounding IPF.

10 MIN1 days ago
Comments
Episode 19: Breathing Life Into Research

Episode 18: Stirring Up A Whole Lot of Science Around Valley Fever

TGen North's Dr. David Engelthaler discusses Valley Fever. We learn why Arizona - with nearly 65% of all Valley Fever cases intheU.S.- is the perfect hotbed for research into this debilitating and potentially lethal disease, and how TGen North is tracking this warm-climate invader and adapting today's technology to provide much needed answers to this age-old problem.

10 MINAUG 21
Comments
Episode 18: Stirring Up A Whole Lot of Science Around Valley Fever

Episode 17: A Deeper Look at Proteomics

Patrick Pirrotte, Ph.D., Assistant Professor of the Cancer and Cell Biology Division and the Director of TGen's Collaborative Center for Translational Mass Spectrometry discusses the role of proteomics in cancer research, and finding new targets for cancer treatment.

4 MINJUL 20
Comments
Episode 17: A Deeper Look at Proteomics

Episode 16: Comparative Oncology Provides Deeper Insight into Cancer

TGen Assistant Professor, Dr. Will Hendricks, discusses comparative oncology, a field of study that in recent years has gained in popularity, as it seeks to integrate information from naturally occurring cancers in pets into what we know about the biology of cancer in humans.

9 MINJUN 21
Comments
Episode 16: Comparative Oncology Provides Deeper Insight into Cancer

Episode 15: MindCrowd—A Study on how the Healthy Brain Works

MindCrowd, launched seven years ago by Dr. Matthew Huentelman, studies the healthy brain. At its core, MindCrowd offers a new way approach scientific research to learn how the brain functions and how genetics influences memory.

11 MINMAY 30
Comments
Episode 15: MindCrowd—A Study on how the Healthy Brain Works

Tiny Microbes A Big Deal for Dr. Sarah Highlander

Microbes out-number the genes in your DNA by more than 1,000 to 1 and together they make up what is known as your microbiome. TGen’s Dr. Sarah K. Highlander, a research professor in the Pathogen and Microbiome Division at TGen North and director of the Clinical Microbiome Service Center, works to understand the microbiome and how it is helping scientists better understand cancer, diabetes and a host of other conditions, including traveler’s diarrhea.

9 MINAPR 17
Comments
Tiny Microbes A Big Deal for Dr. Sarah Highlander

Episode 13: AI and Big Data with Dr. Glen Otero

Dr. Glen Otero, a 20 year veteran of life science industry and an expert in high-performance computing, discusses artificial intelligence, or A.I., and how it addresses the computational needs of the biomedical research community by executing tasks more rapidly and without human error in a fraction of the time. Today, A.I. is used to process complex genomic data sets to accelerate delivery of personalized treatments for cancer and other diseases by turning raw genomic data —such as a human genome sequence— into usable information to predict disease patterns and treatment outcomes.

8 MINMAR 21
Comments
Episode 13: AI and Big Data with Dr. Glen Otero

Episode 12: TGen Talks — Tracking Neurodegenerative Disorders With Biomarkers

In medicine, a biomarker is anything used to determine the presence or development of a particular disease or biological state. They can be used to determine if an injury or disease has occurred, or even if a therapy is working. In this episode, Dr. Kendall Van Keuren-Jensen, a Professor in TGen Neurogenomics Division and Co-Director of TGen’s Center for Noninvasive Diagnostics, discusses how her team is working on ways to use biomarkers — in this case the molecular readout of RNA — as a non-invasive method for studying and treating complex diseases, such as those that affect the nervous system.

9 MINJAN 30
Comments
Episode 12: TGen Talks — Tracking Neurodegenerative Disorders With Biomarkers

Episode 11: Outside Influence: Stimuli, Epigenomics, and Changing Cell Behavior

Nature vs. nurture? How about nature and nature? Dr. Candace Lewis, a postdoctoral fellow in the Huentelman lab at TGen, walks us through a biological regulatory framework known as epigenomics that changes the behavior of our cells due to our life experiences. Dr. Lewis also discusses the resurgence in psychedelic assisted therapy to treat depression and trauma, and her work in Autism.

8 MIN2018 DEC 14
Comments
Episode 11: Outside Influence: Stimuli, Epigenomics, and Changing Cell Behavior

Episode 10: TGen Talks Takeover - Your Best Advice

Helios Scholar Mario Mosqueda asked 10 TGen scientists for their best career advice in an insightful discussion on charting a path in science.

19 MIN2018 OCT 26
Comments
Episode 10: TGen Talks Takeover - Your Best Advice