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Functional Medicine Research with Dr. Nikolas Hedberg

Dr. Nikolas Hedberg, D.C. - Functional Medicine Researcher

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Functional Medicine Research with Dr. Nikolas Hedberg

Functional Medicine Research with Dr. Nikolas Hedberg

Dr. Nikolas Hedberg, D.C. - Functional Medicine Researcher

17
Followers
223
Plays
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About Us

Functional Medicine Research with Dr. Nikolas Hedberg covers cutting-edge research with practical health information that you can actually use in your life to understand your body and get healthy. Dr. Hedberg covers Functional Medicine, thyroid disorders, gut health, autoimmune disease, nutrition and much more. If you’re tired of long-winded podcasts without useful information that actually works then this show is definitely for you.

Latest Episodes

Does Adrenal Fatigue Exist?

“Adrenal Fatigue” is a term used for many years by alternative medicine practitioners but does it exist? This is certainly a term that I have used for some time but not in the way that most practitioners use it. I will use terms at times that are widely searched for on the internet so that I can spread the science behind these terms but it doesn’t necessarily mean that I endorse the term or subscribe to the existence of a condition. There are a few published papers that tackle this very issue that I’ll cover in this article on “adrenal fatigue”. What does the research show about "adrenal fatigue"? The first paper I’d like to mention is entitled, “We are tired of ‘adrenal fatigue’” by Ross et al. The title of this paper quickly gives you the underlying frustration of the authors about this term. This paper is a position statement and not a clinical trial, review, or analysis of any kind. The authors begin by outlining the adrenal fatigue theory and that is doesn’t exist as a defined medical condition. The authors do point out a valid adrenal disorder called adrenal insufficiency which is characterized by insufficient cortisol production after an adrenocorticotropic (ACTH) hormone stimulation test. They also mention Addison’s disease which is true adrenal failure. Interestingly, those who suffer from fatigue actually showed a greater rise in cortisol with an ACTH stimulation test which indicates excessive cortisol production not insufficient cortisol production in those with adrenal insufficiency. And another study actually found no difference in salivary cortisol levels taken throughout the day in two-thirds of healthy subjects compared to those who suffered from fatigue. Dehydroepiandrosterone sulphate (DHEA-S) has also been used as a marker for adrenal fatigue but research has shown this to be unreliable. The most recent systematic review of adrenal fatigue is entitled, “Adrenal fatigue does not exist: a systematic review” by Cadegiani and Kater. The authors searched 3,470 published papers but only 58 of them fulfilled proper criteria for evaluation. Of the 58 studies, only 10 actually used the term “adrenal fatigue” but none of them did any kind of testing to validate this false condition. Some studies tried to use the term “burnout” instead of “adrenal fatigue” but no scientific evidence was presented in these papers. None of the studies in the above review were able to validate any of the functional tests used to assess adrenal hormone production including cortisol and DHEA. Additionally, no valid information was found in these tests to assess HPA axis dysfunction which is one of the hallmarks of “adrenal fatigue”. The authors rightly point out that anytime there is a suspected issue of HPA axis dysfunction, the following must be ruled out as a cause of this dysfunction: 1. Sleep apnea 2. Adrenal insufficiency 3. Mental illness 4. Overwork 5.

16 min4 d ago
Comments
Does Adrenal Fatigue Exist?

How to Overcome Inflammatory Bowel Disease

In this episode of Functional Medicine Research, I interview naturopathic physician Dr. Ilana Gurevich on overcoming inflammatory bowel disease. We had a deep discussion about testing and treatment options for inflammatory bowel diseases including Crohn's disease and ulcerative colitis. We covered diagnostic testing, the pros and cons of stool test markers, probiotics, fiber, digestive enzymes and hydrochloric acid, gut healing nutrients, diets like the Specific Carbohydrate Diet, helminths, and much more. It was a pleasure to have Dr. Gurevich's expertise on inflammatory bowel disease. Below is a transcript on How to Overcome Inflammatory Bowel Disease with Dr. Ilana Gurevich Dr. Hedberg: Well, welcome everyone to "Functional Medicine Research" I'm Dr. Hedberg, really looking forward to my conversation today with Dr. Ilana Gurevich. She is a naturopathic physician and acupuncturist. She graduated from the National University of Natural Medicine in 2007, with her doctorate in naturo...

49 min2 w ago
Comments
How to Overcome Inflammatory Bowel Disease

Selenium, Vitamin D, Glutathione and COVID-19

In this episode of Functional Medicine Research, I interview a very distinguished guest, Ethan Taylor, PhD about his published research on selenium, glutathione, and COVID-19. Dr. Taylor has a wealth of knowledge and research experience on pandemics, selenium, glutathione, vitamin D, viruses, antimicrobial drug resistance, and how human relationships with animals causes so many of our health problems and climate change. I was extremely grateful to have someone like Dr. Taylor on the show to share his expertise. Dr. Hedberg: Well, greetings everyone and welcome to Functional Medicine Research. I'm Dr. Hedberg and I'm really looking forward to my conversation today with Dr. Ethan Will Taylor. And Dr. Taylor is a pharmacologist, computational chemist, and virologist. He has a Bachelor of Science in chemistry from the University of Winnipeg and a PhD in pharmacology and toxicology from the University of Arizona. He began his career as Assistant Professor of Medicinal Chemistry, and late...

58 minSEP 28
Comments
Selenium, Vitamin D, Glutathione and COVID-19

How to Choose the Best Diet for Gut Health

In this episode of Functional Medicine Research, I interview Dr. Liz Lipski in a discussion about how to choose the best therapeutic diet for gut health. We discussed the low FODMAP diet, comprehensive elimination diet, Simple Carbohydrate Diet (SCD), GAPS diet, Paleo diet, histamine, pancreatic elastase and low HCL levels. Liz discussed why we would choose each one of these diets for an individual and what each diet entails. I use all of these diets in my practice so it was nice to have an overview of each diet from one of the top experts in gut health. Dr. Hedberg: Well, welcome everyone to "Functional Medicine Research." I'm Dr. Hedberg. And I'm really looking forward to my conversation today with Dr. Liz Lipski. And Dr. Lipski, she's a Professor and the Director of Academic Development for the Nutrition Programs at Maryland University of Integrative Health. She has a PhD in Clinical Nutrition, two board certifications in nutrition, one in functional medicine, and she's a fellow ...

70 minSEP 14
Comments
How to Choose the Best Diet for Gut Health

5 Quarantine Ideas to Get Healthy and Better Yourself

I’d like to share with you all the things I’ve been doing since the COVID-19 pandemic started to better myself and stay as healthy as possible. I like the quote, “Whenever one door closes, another door opens.” Of course, I miss doing many of the things I normally do to have fun and interact with other people but this has been a time to take advantage of the many opportunities available. No matter what kind of health issues you’re dealing with, some of these ideas can have significant impact on your overall health. Birding Birding or birdwatching has been a growing passion of mine for the last few years but quarantine has given me more time to dedicate to this fascinating hobby. Recent research by Cox and Graston found that people living in neighborhoods with more birds are less likely to suffer from anxiety, depression, and stress. The study participants had lower levels of depression, anxiety, and stress simply by looking at birds, trees, and shrubs. The more birds the partici...

20 minAUG 31
Comments
5 Quarantine Ideas to Get Healthy and Better Yourself

Can COVID-19 Trigger Hashimoto’s Disease?

We have known since the early 1970s that infections can trigger autoimmune diseases and now we have an interesting hypothesis on the potential triggering of Hashimoto’s disease by COVID-19 infection. A recent case study out of Singapore published in the Singapore Medical Journal entitled, “COVID-19 complicated by Hashimoto’s thyroiditis” presents an individual who developed Hashimoto’s thyroiditis after contracting COVID-19. COVID-19 can cause a hyperinflammatory state in the body which is a potential recipe for developing autoimmune disease. The authors begin by pointing out the most current literature on COVID-19 connections to the autoimmune diseases antiphospholipid syndrome, autoimmune thrombocytopenia, autoimmune hemolytic anemia, and Guillain-Barre syndrome. This patient was a 45-year-old Chinese man who developed a non-productive cough and rhinorrhea for one day after exposure to COVID-19 in his dormitory. On the second day of his symptoms he was diagnosed with confirme...

10 minAUG 17
Comments
Can COVID-19 Trigger Hashimoto’s Disease?

What is the Best Diet for Your Gut Microbiome?

It this episode of Functional Medicine Research, I interview Dr. Lucy Mailing in a discussion about the best diet for your gut microbiome. We had a fascinating discussion focused on all of the different diets out there and how they affect the gut microbiome including the ketogenic diet, plant-based diets, high-fat, low FODMAP, and the autoimmune paleo diet. We also talked about fiber, protein, hydrogen sulfide, resistant starch, butyrate, gluten, lectins, stool testing, and whether or not you should take probiotics after taking antibiotics. I think you'll find this conversation quite eye-opening about a number of exciting topics related to the gut micobiome. Below is a transcript on the best diet for your gut micobiome: Dr. Hedberg: Well, welcome, everyone to "Functional Medicine Research". I'm Dr. Hedberg and I'm really looking forward to my conversation today with Dr. Lucy Mailing, PhD. She is a microbiome researcher, educator and passionate scholar of integrative, evidence-based ...

59 minAUG 3
Comments
What is the Best Diet for Your Gut Microbiome?

How to Overcome Trauma with EMDR

In this episode of Functional Medicine Research, I speak with therapist Martina Barnes about how EMDR can help people overcome trauma. I have personally used EMDR with great success in overcoming trauma and I routinely refer for EMDR to help patients get well. One of the most important aspects of practicing functional medicine is understanding how much trauma can be connected to chronic illness. Many patients won't get well until they address their past and how it is affecting their current health issues. All the healthy diets, supplements, exercise, sleep, exposure to nature, community etc. won't be enough if there is underlying trauma history wearing you down. Mental health professionals are severely underutilized yet they should be the first line of therapy for the majority of patients with chronic illness. Unfortunately, they usually end up being the last. This interview should help shed some light on the benefits of EMDR and how it can help you heal and get well for lasting hea...

54 minJUL 20
Comments
How to Overcome Trauma with EMDR

Is Genetic Testing Helpful or Harmful?

In this episode of Functional Medicine Research, I interview Dr. Tommy Wood on the question of whether commercial genetic testing for SNPs is helpful or harmful. This is a topic I have wanted to cover in detail for a long time so when I read Dr. Wood's paper and listened to him speak, I knew his expertise would be invaluable to this conversation. It is important that practitioners and patients know the truth about the current state of genetic testing and whether or not it is scientifically valid or invalid. Dr. Wood has done the necessary research to outline all of the reasons why genetic testing is not a valuable tool in practice and he presents compelling data that it can be more harmful than helpful. As stated in the interview, this is an area that I have never bought into because the science simply doesn't support genetic testing or interventions to address SNPs in clincial practice. I think you'll find this interiew invaluable to your understanding of genetic testing. If you ha...

69 minJUL 6
Comments
Is Genetic Testing Helpful or Harmful?

The 5 Best Adrenal Adaptogens for Fatigue and Stress

Adrenal adaptogens are one of the most commonly prescribed supplements by functional medicine practitioners due to the impact of chronic stress on the majority of sick patients. Stress breaks your body down in every way imaginable so mitigating the negative effects of stress is priority number one in most patients. I’ve been using adrenal adaptogens in my practice for over 15 years now and I’d like to share my favorite adrenal adaptogens that may help you feel better. Adrenal adaptogens can cause negative reactions in some patients so do not take any of these without proper evaluation from a healthcare practitioner to avoid side effects. What is an adrenal adaptogen? An adaptogen has “non-specific” activity and acts by increasing resistance of the organism to a broad spectrum of adverse biological, chemical, and physical factors. Adaptogens act by regulating and normalizing organ and system function in the body. Adaptogens work primarily by affecting the Hypothalamic-Pituitary-A...

22 minJUN 22
Comments
The 5 Best Adrenal Adaptogens for Fatigue and Stress

Latest Episodes

Does Adrenal Fatigue Exist?

“Adrenal Fatigue” is a term used for many years by alternative medicine practitioners but does it exist? This is certainly a term that I have used for some time but not in the way that most practitioners use it. I will use terms at times that are widely searched for on the internet so that I can spread the science behind these terms but it doesn’t necessarily mean that I endorse the term or subscribe to the existence of a condition. There are a few published papers that tackle this very issue that I’ll cover in this article on “adrenal fatigue”. What does the research show about "adrenal fatigue"? The first paper I’d like to mention is entitled, “We are tired of ‘adrenal fatigue’” by Ross et al. The title of this paper quickly gives you the underlying frustration of the authors about this term. This paper is a position statement and not a clinical trial, review, or analysis of any kind. The authors begin by outlining the adrenal fatigue theory and that is doesn’t exist as a defined medical condition. The authors do point out a valid adrenal disorder called adrenal insufficiency which is characterized by insufficient cortisol production after an adrenocorticotropic (ACTH) hormone stimulation test. They also mention Addison’s disease which is true adrenal failure. Interestingly, those who suffer from fatigue actually showed a greater rise in cortisol with an ACTH stimulation test which indicates excessive cortisol production not insufficient cortisol production in those with adrenal insufficiency. And another study actually found no difference in salivary cortisol levels taken throughout the day in two-thirds of healthy subjects compared to those who suffered from fatigue. Dehydroepiandrosterone sulphate (DHEA-S) has also been used as a marker for adrenal fatigue but research has shown this to be unreliable. The most recent systematic review of adrenal fatigue is entitled, “Adrenal fatigue does not exist: a systematic review” by Cadegiani and Kater. The authors searched 3,470 published papers but only 58 of them fulfilled proper criteria for evaluation. Of the 58 studies, only 10 actually used the term “adrenal fatigue” but none of them did any kind of testing to validate this false condition. Some studies tried to use the term “burnout” instead of “adrenal fatigue” but no scientific evidence was presented in these papers. None of the studies in the above review were able to validate any of the functional tests used to assess adrenal hormone production including cortisol and DHEA. Additionally, no valid information was found in these tests to assess HPA axis dysfunction which is one of the hallmarks of “adrenal fatigue”. The authors rightly point out that anytime there is a suspected issue of HPA axis dysfunction, the following must be ruled out as a cause of this dysfunction: 1. Sleep apnea 2. Adrenal insufficiency 3. Mental illness 4. Overwork 5.

16 min4 d ago
Comments
Does Adrenal Fatigue Exist?

How to Overcome Inflammatory Bowel Disease

In this episode of Functional Medicine Research, I interview naturopathic physician Dr. Ilana Gurevich on overcoming inflammatory bowel disease. We had a deep discussion about testing and treatment options for inflammatory bowel diseases including Crohn's disease and ulcerative colitis. We covered diagnostic testing, the pros and cons of stool test markers, probiotics, fiber, digestive enzymes and hydrochloric acid, gut healing nutrients, diets like the Specific Carbohydrate Diet, helminths, and much more. It was a pleasure to have Dr. Gurevich's expertise on inflammatory bowel disease. Below is a transcript on How to Overcome Inflammatory Bowel Disease with Dr. Ilana Gurevich Dr. Hedberg: Well, welcome everyone to "Functional Medicine Research" I'm Dr. Hedberg, really looking forward to my conversation today with Dr. Ilana Gurevich. She is a naturopathic physician and acupuncturist. She graduated from the National University of Natural Medicine in 2007, with her doctorate in naturo...

49 min2 w ago
Comments
How to Overcome Inflammatory Bowel Disease

Selenium, Vitamin D, Glutathione and COVID-19

In this episode of Functional Medicine Research, I interview a very distinguished guest, Ethan Taylor, PhD about his published research on selenium, glutathione, and COVID-19. Dr. Taylor has a wealth of knowledge and research experience on pandemics, selenium, glutathione, vitamin D, viruses, antimicrobial drug resistance, and how human relationships with animals causes so many of our health problems and climate change. I was extremely grateful to have someone like Dr. Taylor on the show to share his expertise. Dr. Hedberg: Well, greetings everyone and welcome to Functional Medicine Research. I'm Dr. Hedberg and I'm really looking forward to my conversation today with Dr. Ethan Will Taylor. And Dr. Taylor is a pharmacologist, computational chemist, and virologist. He has a Bachelor of Science in chemistry from the University of Winnipeg and a PhD in pharmacology and toxicology from the University of Arizona. He began his career as Assistant Professor of Medicinal Chemistry, and late...

58 minSEP 28
Comments
Selenium, Vitamin D, Glutathione and COVID-19

How to Choose the Best Diet for Gut Health

In this episode of Functional Medicine Research, I interview Dr. Liz Lipski in a discussion about how to choose the best therapeutic diet for gut health. We discussed the low FODMAP diet, comprehensive elimination diet, Simple Carbohydrate Diet (SCD), GAPS diet, Paleo diet, histamine, pancreatic elastase and low HCL levels. Liz discussed why we would choose each one of these diets for an individual and what each diet entails. I use all of these diets in my practice so it was nice to have an overview of each diet from one of the top experts in gut health. Dr. Hedberg: Well, welcome everyone to "Functional Medicine Research." I'm Dr. Hedberg. And I'm really looking forward to my conversation today with Dr. Liz Lipski. And Dr. Lipski, she's a Professor and the Director of Academic Development for the Nutrition Programs at Maryland University of Integrative Health. She has a PhD in Clinical Nutrition, two board certifications in nutrition, one in functional medicine, and she's a fellow ...

70 minSEP 14
Comments
How to Choose the Best Diet for Gut Health

5 Quarantine Ideas to Get Healthy and Better Yourself

I’d like to share with you all the things I’ve been doing since the COVID-19 pandemic started to better myself and stay as healthy as possible. I like the quote, “Whenever one door closes, another door opens.” Of course, I miss doing many of the things I normally do to have fun and interact with other people but this has been a time to take advantage of the many opportunities available. No matter what kind of health issues you’re dealing with, some of these ideas can have significant impact on your overall health. Birding Birding or birdwatching has been a growing passion of mine for the last few years but quarantine has given me more time to dedicate to this fascinating hobby. Recent research by Cox and Graston found that people living in neighborhoods with more birds are less likely to suffer from anxiety, depression, and stress. The study participants had lower levels of depression, anxiety, and stress simply by looking at birds, trees, and shrubs. The more birds the partici...

20 minAUG 31
Comments
5 Quarantine Ideas to Get Healthy and Better Yourself

Can COVID-19 Trigger Hashimoto’s Disease?

We have known since the early 1970s that infections can trigger autoimmune diseases and now we have an interesting hypothesis on the potential triggering of Hashimoto’s disease by COVID-19 infection. A recent case study out of Singapore published in the Singapore Medical Journal entitled, “COVID-19 complicated by Hashimoto’s thyroiditis” presents an individual who developed Hashimoto’s thyroiditis after contracting COVID-19. COVID-19 can cause a hyperinflammatory state in the body which is a potential recipe for developing autoimmune disease. The authors begin by pointing out the most current literature on COVID-19 connections to the autoimmune diseases antiphospholipid syndrome, autoimmune thrombocytopenia, autoimmune hemolytic anemia, and Guillain-Barre syndrome. This patient was a 45-year-old Chinese man who developed a non-productive cough and rhinorrhea for one day after exposure to COVID-19 in his dormitory. On the second day of his symptoms he was diagnosed with confirme...

10 minAUG 17
Comments
Can COVID-19 Trigger Hashimoto’s Disease?

What is the Best Diet for Your Gut Microbiome?

It this episode of Functional Medicine Research, I interview Dr. Lucy Mailing in a discussion about the best diet for your gut microbiome. We had a fascinating discussion focused on all of the different diets out there and how they affect the gut microbiome including the ketogenic diet, plant-based diets, high-fat, low FODMAP, and the autoimmune paleo diet. We also talked about fiber, protein, hydrogen sulfide, resistant starch, butyrate, gluten, lectins, stool testing, and whether or not you should take probiotics after taking antibiotics. I think you'll find this conversation quite eye-opening about a number of exciting topics related to the gut micobiome. Below is a transcript on the best diet for your gut micobiome: Dr. Hedberg: Well, welcome, everyone to "Functional Medicine Research". I'm Dr. Hedberg and I'm really looking forward to my conversation today with Dr. Lucy Mailing, PhD. She is a microbiome researcher, educator and passionate scholar of integrative, evidence-based ...

59 minAUG 3
Comments
What is the Best Diet for Your Gut Microbiome?

How to Overcome Trauma with EMDR

In this episode of Functional Medicine Research, I speak with therapist Martina Barnes about how EMDR can help people overcome trauma. I have personally used EMDR with great success in overcoming trauma and I routinely refer for EMDR to help patients get well. One of the most important aspects of practicing functional medicine is understanding how much trauma can be connected to chronic illness. Many patients won't get well until they address their past and how it is affecting their current health issues. All the healthy diets, supplements, exercise, sleep, exposure to nature, community etc. won't be enough if there is underlying trauma history wearing you down. Mental health professionals are severely underutilized yet they should be the first line of therapy for the majority of patients with chronic illness. Unfortunately, they usually end up being the last. This interview should help shed some light on the benefits of EMDR and how it can help you heal and get well for lasting hea...

54 minJUL 20
Comments
How to Overcome Trauma with EMDR

Is Genetic Testing Helpful or Harmful?

In this episode of Functional Medicine Research, I interview Dr. Tommy Wood on the question of whether commercial genetic testing for SNPs is helpful or harmful. This is a topic I have wanted to cover in detail for a long time so when I read Dr. Wood's paper and listened to him speak, I knew his expertise would be invaluable to this conversation. It is important that practitioners and patients know the truth about the current state of genetic testing and whether or not it is scientifically valid or invalid. Dr. Wood has done the necessary research to outline all of the reasons why genetic testing is not a valuable tool in practice and he presents compelling data that it can be more harmful than helpful. As stated in the interview, this is an area that I have never bought into because the science simply doesn't support genetic testing or interventions to address SNPs in clincial practice. I think you'll find this interiew invaluable to your understanding of genetic testing. If you ha...

69 minJUL 6
Comments
Is Genetic Testing Helpful or Harmful?

The 5 Best Adrenal Adaptogens for Fatigue and Stress

Adrenal adaptogens are one of the most commonly prescribed supplements by functional medicine practitioners due to the impact of chronic stress on the majority of sick patients. Stress breaks your body down in every way imaginable so mitigating the negative effects of stress is priority number one in most patients. I’ve been using adrenal adaptogens in my practice for over 15 years now and I’d like to share my favorite adrenal adaptogens that may help you feel better. Adrenal adaptogens can cause negative reactions in some patients so do not take any of these without proper evaluation from a healthcare practitioner to avoid side effects. What is an adrenal adaptogen? An adaptogen has “non-specific” activity and acts by increasing resistance of the organism to a broad spectrum of adverse biological, chemical, and physical factors. Adaptogens act by regulating and normalizing organ and system function in the body. Adaptogens work primarily by affecting the Hypothalamic-Pituitary-A...

22 minJUN 22
Comments
The 5 Best Adrenal Adaptogens for Fatigue and Stress
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