In part 2 we talk about the work-up for rapidly progressive dementias, and then run through some interesting cases pulled from the literature and personal experience.
We're very fortunate to have the wonderful Professor Amy Brodtmann talk to us about rapidly progressive dementias. In part one we talk about the different differentials you should be thinking about when you come across these cases.
A discussion of the diagnosis of MS with Professor Tomas Kalincik – we run through the principles behind the McDonald criteria, when to apply them, how to use MRI, oligoclonal bands, misdiagnosis and red flags. Following this, we go through some cases ranging from barn-door MS to some trickier cases. The whole podcast is filled with pearls!
A/Prof Richard Stark takes us through his approach to radiculopathy. A/Prof Stark has decades of experience in clinical neurology and teaching - and it really shows. This one is packed full of pearls.
Thanks to Dr John Williamson for lending us this episode that he recorded for another clinically-focused neurology podcast - Neuropodcases. Listen in as he chats with Associated Professor Nawaf Yassi about intracerebral haemorrhage. They discuss hypertensive ICH, intraventricular extension, amyloid ICH, role of surgery, how to approach antithrombotics and ICH in younger patients. It's a fascinating conversation with plenty of clinical pearls. We would highly encourage you to have a look at John's podcast over at https://www.neuropodcases.co.uk/ where you will also find imaging referred to in this podcast.
Expert neuroophthalmologist Dr Anthony Fok takes us through the common but commonly vexing condition of intracranial atherosclerosis. We talk about how to assess IIH patients, how to manage them medically, when surgery is required, what to do when they don't tolerate the usual medications and more!
Dr Chris Kyndt lends his wisdom on how to deal with those tricky referrals regarding confusion and delirium. Which ones do you LP? When should you immunosuppress on spec. Listen in to find out.
We run through the primary progressive aphasias with A/Prof David Darby. Listen in as David demystifies how to differentiate logopenic aphasia, semantic variant and non-fluent variant. A long episode but absolutely packed full of pearls about how to take a history, examine, use cognitive tools and employ imaging in these patients. Then we go through some cases where David shows us how it's done.
We discuss all sorts of quandaries and myths related to lumbar punctures and CSF interpretation with Dr Prashanth Ramachandran. Specific topics covered include: lumbar punctures on antiplatelets/anticoagulants, lumbar punctures in the setting of intracranial masses, post-LP leptomeningeal enhancement, investigation of acute meningoencephalitis, investigation of chronic meningoencephalitis, acellular elevated protein, chronic idiopathic meningitis, post-ictal lymphocytic pleocytosis and HaNDL.
Professor Vincent Thijs takes us through his approach to working up stroke patients for secondary causes. We discuss embolic stroke of undetermined source (ESUS), aortic arch atheroma, intracranial atherosclerosis, patent foramen ovale, vasculitis, which investigations are the highest yield and general approaches to different types of patients. Enjoy!