On March 3, 2022, we chatted with Dr. Bennett Novitch, about the development of cortical circuits, the replication of cortical development using organoids formed from human pluripotent stem cells, and the changes in function seen in cortical organoids with mutations that produce an epileptic condition in humans. Dr. Novitch is Professor of Neurobiology and the Broad Center of Regenerative Medicine and Stem Cell Research at the David Geffen School of Medicine at UCLA. https://novitchlab.com/ We were joined by Dr. Jenny Hsieh, Professor and Chair of the Department of Neuroscience, Developmental and Regenerative Biology, UTSA. https://hsiehlab.org/ Host: Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology, UTSA. Neuroscientists Talk Shop podcast: https://tinyurl.com/yxatz6fq​ UTSA Neurosciences Institute: https://neuroscience.utsa.edu​ UTSA Brain Health Consortium https://www.utsa.edu/bhc The University of Texas San Antonio: https://www.utsa.edu